單細胞測序技術服務 單細胞全轉錄組測序 |
NGS測序技術服務 DRIP-seq |
基因芯片技術服務 Small RNA修飾芯片 m6A單堿基分辨率芯片 mRNA&lncRNA表觀轉錄組芯片 circRNA表觀轉錄組芯片 |
NGS測序技術服務 RNA m6A甲基化測序(MeRIP Seq) |
LC-MS mRNA堿基修飾檢測 tRNA堿基修飾檢測 |
PCR技術服務 MeRIP-PCR技術服務 m6A絕對定量RT-PCR技術服務 m6A單堿基位點PCR(MazF酶切法)技術服務 |
基因芯片技術服務 DNA甲基化芯片 DNA羥甲基化芯片 ChIP-chip |
NGS測序技術服務 DNA甲?;奏?5fc)修飾測序 DNA 5hmC 測序(化學法) DNA甲基化測序 DNA羥甲基化測序 染色質免疫共沉淀測序 |
PCR技術服務 MeDIP-qPCR hMeDIP-qPCR ChIP-qPCR |
蛋白相對定量 TMT標記定量技術 非標定量技術 |
蛋白修飾 TMT標記定量磷酸化 非標定量磷酸化 |
RNA/蛋白-蛋白相互作用 RNA-蛋白相互作用 蛋白-蛋白相互作用 |
METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis , Molecular Cancer . 2022NEW!
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by
upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer . Molecular
Cancer . 2022NEW!
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its
stability to facilitate nasopharyngeal carcinoma growth and metastasis . Cell
Death & Differentiation . 2022NEW!
METTL3 promotes colorectal carcinoma progression by regulating the m6A–CRB3–Hippo axis . Journal of Experimental & Clinical Cancer Research . 2022NEW!
m6A‐mediated regulation of PBX1‐GCH1 axis promotes gastric cancer proliferation and metastasis by elevating tetrahydrobiopterin levels . Cancer Communications . 2022NEW!
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression . Oncogene . 2022NEW!
The Combined Effects of circRNA Methylation Promote Pulmonary Fibrosis . American Journal of Respiratory Cell and Molecular Biology . 2022NEW!
ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1 . Theranostics . 2021
RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent . Journal of Experimental & Clinical Cancer Research . 2021
ALKBH5-mediated m6A mRNA Methylation Governs Human Embryonic Stem Cell Cardiac Commitment . Molecular Therapy-Nucleic Acids . 2021
ALKBH5 suppresses tumor progression via an m 6 A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma . Cell Death & Disease . 2021
RBM15-mediated N6-methyladenosine modification affects COVID-19 severity by regulating the expression of multitarget genes . Cell Death & Disease . 2021
The potential roles of m6 A modification in regulating the inflammatory response in microglia . Journal of Neuroinflammation . 2021
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation of Parp10 mRNA . Nature Cell Biology . 2020
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer " . Molecular cancer . 2020
NADP modulates RNA m 6 A methylation and adipogenesis via enhancing FTO activity . Nature Chemical Biology . 2020
N6-Methyladenosine Modification of Fatty Acid Amide Hydrolase Messenger RNA in Circular RNA STAG1-Regulated Astrocyte Dysfunction and Depressive-like Behaviors. . Biological Paychiatry . 2020
SIRT1 regulates N6‐methyladenosine RNA modification in hepatocarcinogenesis by inducing RANBP2‐dependent FTO SUMOylation . Hepatology . 2020
m6A methylation of precursor-miR-320/RUNX2 controls osteogenic potential of bone marrow-derived mesenchymal stem cells . Molecular Therapy-Nucleic Acids . 2019
KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3 . Molecular Cancer . 2019
METTL3-mediated m6A modification of HDGF mRNA promotes gastric cancer progression and has prognostic significance. . Gut . 2019
Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice . Epigenomics . 2019